Cardiogen
Cardiogen is a synthetic short peptide in the group known as peptide bioregulators, studied for tissue-specific effects on heart tissue. Its only peer-reviewed study identified in PubMed tested it in organotypic cultures of rat heart explants. No PubChem record exists for it, published data are very limited, and it is not an FDA-approved drug.
Last reviewed · Identity data matched to PubChem · 1 peer-reviewed sources
Key facts
- Class: short peptide bioregulator; synthetic peptide
- Studied for tissue-specific effects on heart (cardiac) tissue
- No PubChem record; formula and molecular weight are not confirmed by a cited source
- Evidence base: one rat organotypic tissue-culture study in this source set
- Tested alongside bronchogen, prostamax and pancragen in explant cultures
- Regulatory status: not approved by the FDA
Chemical Identity
| Compound type | Peptide |
|---|
What Is Cardiogen?
Cardiogen is a synthetic short peptide classed among the peptide bioregulators, a group of small peptides studied for organ- or tissue-specific activity. In the one peer-reviewed study identified, it was tested on heart tissue alongside related peptides aimed at lung, prostate and pancreatic tissue.[1] In that study each peptide was matched to its own target tissue, with Cardiogen paired with heart explants, bronchogen with lung, prostamax with prostate and pancragen with pancreas.[1]
Peer-reviewed data on Cardiogen are very limited. A PubMed search returned a single study that clearly examines this compound. Most other results for the name concerned unrelated topics, such as a rubidium-82 generator system used in cardiac PET imaging and clinical papers on cardiogenic shock and cardiomyopathy. This page covers only what the relevant study and confirmed identity sources support.
Chemical Structure and Molecular Identity
Cardiogen’s exact chemical identity cannot be confirmed from the sources available for this page. PubChem has no record for the compound, so there is no verified molecular formula, molecular weight, CAS number or InChIKey to report.
The one relevant study describes Cardiogen only as a synthetic peptide and does not state its amino acid sequence in the abstract.[1] For that reason this page does not list a sequence. Researchers comparing materials sold under this name should rely on analytical data that report a sequence and a measured mass, since the name alone does not establish structure.
What the Published Literature Covers
The published record on Cardiogen consists of one rat tissue-culture study that tested whether it acts selectively on heart tissue. The 2006 study by Zakutskii, Chalisova, Ryzhak and colleagues, published in a gerontology journal, examined four synthetic peptides: Cardiogen, bronchogen, prostamax and pancragen.[1]
- Model: organotypic cultures of explants from the heart, lungs, prostate gland and pancreas of young (3-week-old) and aged (18-month-old) rats.[1]
- Finding: at the effective concentration tested, each peptide stimulated growth in its corresponding tissue culture compared with control explants, in both young and aged rats.[1]
- Interpretation: the authors described the peptides as bioregulators with tissue-specific effects in explant culture.[1]
Organotypic explant growth is an early laboratory screen. It does not show how a peptide behaves in a living animal or a person. No animal studies, human trials, receptor data, pharmacokinetic data or toxicology data on Cardiogen were found in the PubMed results reviewed for this page.
Because no PubChem record defines Cardiogen, researchers typically verify sequence and measured mass using HPLC and mass spectrometry data on a certificate of analysis.
Regulatory and Research Status
Cardiogen is not approved by the US Food and Drug Administration and is handled as a research compound in the United States. With a single explant-culture study and no PubChem record, it is among the least characterized peptides in the bioregulator group.
Claims about effects on heart function in living systems are not supported by peer-reviewed data in this source set. Any further statements about its structure or activity would need confirmation from new published studies or verified analytical records.
Commonly Supplied Research Formats
Cardiogen is listed by 3 of the 11 major U.S. research-peptide suppliers we track. The most commonly listed formats are:
- 20mg
Supplier catalog survey, October 2026. Quantities refer to net peptide per vial as labeled.
Frequently Asked Questions
What is Cardiogen?
Cardiogen is a synthetic short peptide in the group known as peptide bioregulators. In the one peer-reviewed study identified, it stimulated growth of rat heart tissue explants in organotypic culture compared with controls. No PubChem record exists for it, and its published literature is limited to that single laboratory study.
What is the molecular weight of Cardiogen?
A verified molecular weight for Cardiogen is not available. PubChem has no record for the compound, and the one peer-reviewed study identified does not report its formula or sequence in the abstract. Researchers typically rely on mass spectrometry data from the specific material they are evaluating to establish its identity.
Is Cardiogen FDA approved?
No. Cardiogen is not approved by the US Food and Drug Administration for any use and is handled as a research compound in the United States. Its peer-reviewed record consists of a single rat tissue-culture study, with no published animal studies or human clinical trials identified in PubMed.
What does the research on Cardiogen show?
The only study identified tested Cardiogen in organotypic cultures of heart explants from young and aged rats. It stimulated explant growth compared with controls, as did related peptides in their matching tissues. This is an early in-vitro screen from one research group, and it does not show effects in living animals or people.
References
- Zakutskiĭ AN, Chalisova NI, Ryzhak GA, et al. [The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats]. Advances in gerontology = Uspekhi gerontologii 2006. PMID 17152728
Related Compounds
This profile summarizes chemical data and peer-reviewed literature for educational and laboratory-research reference. It is not medical advice, and nothing here describes or recommends use in humans or animals. How we source and verify data.